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Structure of 7087-65-2
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1-Bromo-3-fluoro-5-nitrobenzene features a trifunctional aryl scaffold with complementary electronic and steric profiles. The electron-deficient ring facilitates cross-coupling reactions, while the bromo and fluoro substituents enable sequential functionalization. This compound serves as a key intermediate in the synthesis of advanced pharmaceuticals and functional materials.
1-Bromo-3-fluoro-5-nitrobenzene serves as a versatile building block in medicinal chemistry and materials science, enabling sequential cross-coupling reactions due to its orthogonal reactivity profile. The bromo group facilitates palladium-catalyzed coupling, while the fluoro and nitro substituents offer directed functionalization potential and enhanced metabolic stability in bioactive scaffolds. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: