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CS-W001157 4
Total: USD 88.00

1-(2-Methoxyphenyl)ethan-1-amine

  • CAS No. 40023-74-3

  • Cat. No. CS-0089766
  • Purity≥98%
  • MDL No.MFCD00593475

*For research and further manufacturing use only, not for direct human use.

1-(2-Methoxyphenyl)ethan-1-amine|CS-0089766

Structure of 40023-74-3

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General Information

  • CAS No. 40023-74-3
  • Cat. No. CS-0089766
  • Purity ≥98%
  • MDL No. MFCD00593475
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO
  • Molecular Weight 151.21
  • Synonym(s) 1-(2-Methoxyphenyl)ethylamine
  • SMILES NC(C1=CC=CC=C1OC)C

Description

1-(2-Methoxyphenyl)ethan-1-amine features a benzene ring bearing a methoxy group at the ortho position and an ethylamine side chain, enabling strong π-stacking and hydrogen-bonding interactions. This scaffold integrates readily into bioactive molecules and serves as a key building block in medicinal chemistry for targeted receptor modulation.

Application

1-(2-Methoxyphenyl)ethan-1-amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-methoxy-substituted aryl group offers enhanced solubility and metabolic stability, while the primary amine facilitates straightforward derivatization via acylation, alkylation, and coupling reactions. The compound exhibits good bench stability and ease of purification, making it suitable for scale-up applications in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314-H331-H412
Precautionary Statements : P261-P273-P280

Quality Control

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.7149
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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