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Structure of 40137-29-9
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4-Chloro-2-methylbenzaldehyde features a chlorine atom at the para position and a methyl group at the ortho position relative to the aldehyde, creating a sterically hindered, electron-deficient aromatic ring. This configuration enhances reactivity in nucleophilic addition and coupling reactions, particularly in pharmaceutical synthesis and agrochemical intermediates. The compound exhibits bench-stable handling characteristics under standard conditions.
4-Chloro-2-methylbenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of substituted aromatic scaffolds. Its ortho-methyl and para-chloro substituents provide distinct electronic and steric modulation, enhancing reactivity in nucleophilic additions, condensation reactions, and transition-metal-catalyzed couplings. The aldehyde functionality offers high synthetic versatility for downstream transformations including imine formation, reductive amination, and Ullmann-type coupling processes. Bench-stable and readily purified by distillation or recrystallization, it supports scalable applications in both research and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: