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CS-W001157 4
Total: USD 88.00

3-Methoxypyrazine-2-carboxylic acid

  • CAS No. 40155-47-3

  • Cat. No. CS-W018862
  • Purity≥98%
  • MDL No.MFCD10697766
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Methoxypyrazine-2-carboxylic acid|CS-W018862

Structure of 40155-47-3

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Description

3-Methoxypyrazine-2-carboxylic acid features a pyrazine core functionalized with methoxy and carboxylic acid groups, enabling direct incorporation into bioactive scaffolds. This electron-deficient heterocycle serves as a key building block in medicinal chemistry, offering enhanced solubility and metabolic stability. The molecule integrates readily into drug candidates requiring polar, rigid frameworks for target engagement.

Application

3-Methoxypyrazine-2-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyrazine-based scaffolds prevalent in agrochemical and medicinal chemistry. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions, while the methoxy group provides moderate electronic modulation and orthogonal reactivity. The compound exhibits good bench stability and is readily purified by recrystallization or chromatography, supporting its use in scalable synthetic routes and API intermediate development.

General Information

  • CAS No. 40155-47-3
  • Cat. No. CS-W018862
  • Purity ≥98%
  • MDL No. MFCD10697766
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆N₂O₃
  • Molecular Weight 154.12
  • Synonym(s) None
  • SMILES COC1=C(N=CC=N1)C(O)=O

Computational Chemistry Data

  • TPSA   72.31
  • LogP   0.1834
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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