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Structure of 403-20-3
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3-Fluoro-4-methoxybenzoic acid features a strategically positioned fluorine atom and methoxy group on the aromatic ring, enhancing electronic modulation and solubility. This combination enables efficient integration into pharmaceutical intermediates and bioactive scaffolds under standard conditions.
3-Fluoro-4-methoxybenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive molecules through established coupling and functionalization reactions. Its ortho-fluoro and para-methoxy substituents provide enhanced metabolic stability and modulate electronic properties, while the carboxylic acid group facilitates direct amidation, esterification, or Suzuki-Miyaura coupling. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: