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Structure of 403-21-4
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3-Fluoro-4-nitrobenzenecarboxylic acid features a strategically positioned fluorine atom and nitro group on the aromatic ring, enabling selective functionalization in synthetic routes. This electron-deficient scaffold integrates readily into pharmaceutical intermediates and advanced materials, offering enhanced reactivity under standard conditions.
3-Fluoro-4-nitrobenzoic acid serves as a versatile building block in medicinal chemistry and materials science, enabling the synthesis of functionalized heterocycles and conjugated systems. Its dual electron-withdrawing groups (nitro and carboxylic acid) enhance reactivity in nucleophilic aromatic substitution and coupling reactions. The fluorine substituent provides site-specific derivatization potential via selective displacement. This compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis and downstream functionalization in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: