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Structure of 404-90-0
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3-Fluoro-4-methoxylphenylacetonitrile features a strategically positioned nitrile group flanked by electron-withdrawing fluorine and electron-donating methoxy substituents, enabling precise tuning of reactivity in synthetic transformations. This aromatic acetonitrile derivative offers enhanced stability and solubility under standard conditions, facilitating efficient incorporation into pharmaceutical intermediates and functional materials.
3-Fluoro-4-methoxyphenylacetonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles and pharmaceutical intermediates. Its orthogonal functionality—fluorine for metabolic stability, methoxy for electronic modulation, and nitrile for downstream transformations—facilitates diverse coupling reactions and ring-forming processes under standard conditions. The compound exhibits excellent bench stability and is amenable to purification via standard chromatographic methods, making it well-suited for scalable synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301+H311+H331
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: