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CS-W001157 4
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1-Bromo-3-(2-bromoethyl)benzene

  • CAS No. 40422-70-6

  • Cat. No. CS-0171086
  • Purity≥98%
  • MDL No.MFCD07784359

*For research and further manufacturing use only, not for direct human use.

1-Bromo-3-(2-bromoethyl)benzene|CS-0171086

Structure of 40422-70-6

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General Information

  • CAS No. 40422-70-6
  • Cat. No. CS-0171086
  • Purity ≥98%
  • MDL No. MFCD07784359
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈Br₂
  • Molecular Weight 263.96
  • Synonym(s) None
  • SMILES C1=CC(=CC(=C1)Br)CCBr

Description

1-Bromo-3-(2-bromoethyl)benzene features a benzene ring bearing a bromo substituent at the meta position and a 2-bromoethyl group at the para position, enabling dual functionalization. This bifunctional scaffold supports efficient cross-coupling and cyclization reactions in synthetic organic chemistry.

Application

1-Bromo-3-(2-bromoethyl)benzene serves as a versatile dihalogenated building block for constructing functionalized aromatic scaffolds. The bromoethyl side chain enables efficient alkylation or palladium-catalyzed coupling reactions, while the ortho-bromophenyl group supports further functionalization via cross-coupling or nucleophilic substitution. Its bench-stable nature and compatibility with standard synthetic protocols facilitate reliable use in medicinal chemistry and materials synthesis workflows.

Synthesis

  • Route1

    References

    • Blanckaert; Burvenich; Devos; Slegers Journal of Labelled Compounds and Radiopharmaceuticals, 2007 , vol. 50, # 3 p. 183 - 188
  • Route2
    • null|null
      75-25-2
    • Spiro[2.4]hepta-4,6-diene|CS-0259439
      765-46-8
    • ~58%
    • In-stock
      1-Bromo-3-(2-bromoethyl)benzene|CS-0171086
      40422-70-6

    References

    • Molchanov, A. P.; Kostikov, R. R. Journal of Organic Chemistry USSR (English Translation), 1992 , vol. 28, # 6.1 p. 935 - 937 Zhurnal Organicheskoi Khimii, 1992 , vol. 28, # 6 p. 1197 - 1199
  • Route3
    • null|null
      64723-45-1
    • ~%
    • In-stock
      1-Bromo-3-(2-bromoethyl)benzene|CS-0171086
      40422-70-6

    References

    • DePuy; Froemsdorf Journal of the American Chemical Society, 1957 , vol. 79, p. 3710

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3082
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H317-H411
Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.3865
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   2

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