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Structure of 404827-75-4
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6-Fluoro-1H-indazol-3-amine features a fluorinated indazole core with a primary amine at the 3-position, enabling direct incorporation into diverse heterocyclic scaffolds. The electron-deficient aromatic system enhances reactivity in transition-metal-catalyzed couplings, while the fluorine substituent improves metabolic stability and membrane permeability. This bench-stable compound serves as a key building block for bioactive molecule synthesis.
6-Fluoro-1H-indazol-3-amine serves as a versatile building block for the synthesis of bioactive heterocycles, particularly in medicinal chemistry and agrochemical research. Its electron-deficient indazolyl core enables efficient coupling reactions via the primary amine, while the fluorine substituent enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative scaffold elaboration and high-throughput screening campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: