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CS-W001157 4
Total: USD 88.00

3,4-Difluorostyrene,98% (stabilized with TBC)

  • CAS No. 405-03-8

  • Cat. No. CS-0113814
  • Purity98% (stabilized with TBC)
  • MDL No.MFCD09038471
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3,4-Difluorostyrene,98% (stabilized with TBC)|CS-0113814

Structure of 405-03-8

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Description

3,4-Difluorostyrene, 98% (stabilized with TBC) features a dual fluorine substitution at the ortho positions of the phenyl ring, enhancing electron deficiency and metabolic stability. The para-vinyl group enables efficient coupling in cross-coupling reactions. Stabilized with TBC to inhibit polymerization during storage and handling. Bench-stable under standard conditions.

Application

3,4-Difluorostyrene (98%, stabilized with TBC) serves as a valuable building block for fluorinated aromatic systems, enabling efficient incorporation of ortho-difluoro substitution into pharmaceutical and agrochemical scaffolds. The stabilizer (TBC) enhances shelf stability and handling safety, while the vinyl functionality facilitates robust cross-coupling reactions, including Suzuki-Miyaura and Heck processes. Its bench-stable nature and compatibility with standard reaction conditions make it a practical choice for synthetic chemists developing fluorinated heterocycles and bioactive molecules.

General Information

  • CAS No. 405-03-8
  • Cat. No. CS-0113814
  • Purity 98% (stabilized with TBC)
  • MDL No. MFCD09038471
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆F₂
  • Molecular Weight 140.13
  • Synonym(s) 4-Ethenyl-1,2-difluorobenzene
  • SMILES FC1=CC(C=C)=CC=C1F

Computational Chemistry Data

  • TPSA   0
  • LogP   2.6078
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

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