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Structure of 405-66-3
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4-Fluoro-N-methylbenzylamine features a fluorinated aromatic ring paired with a tertiary amine side chain, delivering enhanced metabolic stability and improved membrane permeability. This combination enables efficient incorporation into bioactive molecules for medicinal chemistry campaigns targeting CNS receptors and kinase inhibitors.
4-Fluoro-N-methylbenzylamine serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted benzylamine scaffolds. Its fluorinated aromatic ring enhances metabolic stability and modulates electronic properties, while the N-methyl group provides favorable lipophilicity and improved membrane permeability. The amine functionality facilitates straightforward derivatization via alkylation, acylation, or reductive amination, supporting rapid library synthesis for target-directed compound development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1760
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H227-H315-H317-H318-H335
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Precautionary Statements : P210-P261-P264-P271-P272-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: