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Structure of 40733-27-5
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3’-O-t-Butyldimethylsilylthymidine features a protected 3’-hydroxyl group, enabling stable storage and selective coupling in oligonucleotide synthesis. The silyl moiety provides robust resistance to hydrolysis under standard conditions while allowing facile deprotection with fluoride sources. This derivative facilitates efficient chain elongation in nucleoside-based workflows.
3’-O-Tert-butyldimethylsilylthymidine serves as a protected thymidine building block for nucleoside synthesis, offering enhanced stability and ease of purification. The silyl group enables selective 3’-functionalization while tolerating standard coupling conditions, facilitating efficient oligonucleotide assembly and protecting against degradation during storage and handling.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: