Boc-L-Homoserine lactone

Name: Boc-L-Homoserine lactone
Brand: ChemScene
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CAS No. 40856-59-5
Cat. No. CS-W018939
Purity≥97%
MDL No.MFCD04973958

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 40856-59-5

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Description

Boc-L-Homoserine lactone features a protected hydroxyl-bearing amino acid scaffold with a stable cyclic ester core. This bench-stable derivative enables direct incorporation into peptide synthesis workflows without side-chain interference, offering reliable access to homoserine-containing sequences in biopharmaceutical and chemical biology applications.

Application

Boc-L-Homoserine lactone serves as a versatile building block in peptide and heterocyclic synthesis, enabling efficient access to β-lactone-containing scaffolds. Its bench-stable Boc protection offers excellent functional group tolerance, facilitating subsequent transformations such as ring-opening reactions and coupling protocols. Widely employed in medicinal chemistry campaigns, it functions as a key intermediate for constructing bioactive motifs and cyclic peptide analogs with predictable reactivity under standard conditions.

General Information

CAS No. 40856-59-5
Cat. No. CS-W018939
Purity ≥97%
MDL No. MFCD04973958
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₅NO₄
Molecular Weight 201.22
Synonym(s) tert-Butyl [(3S)-2-oxotetrahydrofuran-3-yl]carbamate
SMILES CC(C)(C)OC(=O)N[C@H]1CCOC1=O

Computational Chemistry Data

TPSA 64.63
LogP 0.8266
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydrofuran compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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Boc-L-Homoserine lactone

CAS No. 40856-59-5

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