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CS-W001157 4
Total: USD 88.00

5-(4-Chlorophenyl)-2-furoic acid

  • CAS No. 41019-45-8

  • Cat. No. CS-0117740
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-(4-Chlorophenyl)-2-furoic acid|CS-0117740

Structure of 41019-45-8

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General Information

  • CAS No. 41019-45-8
  • Cat. No. CS-0117740
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₇ClO₃
  • Molecular Weight 222.62
  • Synonym(s) IFLAB-BB F0722-7390
  • SMILES O=C(O)C1=CC=C(C2=CC=C(Cl)C=C2)O1

Description

5-(4-Chlorophenyl)-2-furoic acid features a conjugated furoic acid core linked to an electron-deficient 4-chlorophenyl group, enabling efficient integration into heterocyclic frameworks. This bench-stable, moisture-tolerant reagent facilitates direct coupling reactions in medicinal chemistry and materials synthesis under standard conditions.

Application

5-(4-Chlorophenyl)-2-furoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its conjugated furoic acid core exhibits good bench stability and facilitates efficient coupling reactions, while the 4-chlorophenyl substituent offers enhanced reactivity in palladium-catalyzed transformations. The carboxylic acid group enables straightforward derivatization for structure-activity studies.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.44
  • LogP   3.2982
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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