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Structure of 6051-13-4
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2-Cyclohexylpropanoic acid features a sterically hindered alkyl chain fused to a cyclohexyl ring, delivering enhanced metabolic stability and lipophilicity. This structural motif enables efficient integration into bioactive scaffolds for medicinal chemistry applications, particularly in optimizing pharmacokinetic profiles of target-directed molecules.
2-Cyclohexylpropanoic acid serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through established coupling and functionalization protocols. Its rigid cyclohexyl substituent provides enhanced metabolic stability and defined stereochemistry, while the carboxylic acid group facilitates direct amidation, esterification, and derivatization under standard conditions. Bench-stable and amenable to purification via recrystallization or chromatography, it functions effectively in both small-molecule discovery and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: