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Structure of 41337-81-9
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Ethyl 6-(hydroxymethyl)picolinate features a hydroxymethyl group at the 6-position of the picolinate scaffold, enabling direct functionalization for bioconjugation or derivatization. This bench-stable ester integrates readily into synthetic sequences requiring polar, oxygen-rich side chains. The para-hydroxyalkyl moiety enhances solubility and provides a handle for further chemical modification.
Ethyl 6-(hydroxymethyl)picolinate serves as a versatile building block for heterocyclic synthesis, enabling efficient access to bioactive scaffolds through standard functional group transformations. The pendant hydroxymethyl group facilitates oxidation to carboxylic acid, reduction to alcohol, or derivatization via Mitsunobu and Williamson ether reactions. Its stability under routine bench conditions and compatibility with common protecting group strategies make it a practical choice for medicinal chemistry campaigns requiring picolinic acid derivatives.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: