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Structure of 893738-68-6
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5-Cyclopropylpyridin-2-amine features a cyclopropyl group at the 5-position of a pyridine ring, enhancing lipophilicity and metabolic stability. The primary amine at the 2-position enables direct functionalization in medicinal chemistry. This scaffold integrates readily into kinase inhibitors and CNS-targeted compounds due to favorable solubility and membrane permeability under standard conditions.
5-Cyclopropylpyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling reactions. Its pyridine core offers favorable electronic properties and hydrogen-bonding capacity, while the cyclopropyl group enhances metabolic stability and modulates lipophilicity. The amine functionality facilitates straightforward derivatization, and the compound exhibits excellent bench stability and compatibility with common purification methods.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: