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CS-W001157 4
Total: USD 88.00

2,4-Dichlorothiazole

  • CAS No. 4175-76-2

  • Cat. No. CS-W018061
  • Molecule weight154.01
  • Purity≥97%
  • MDL No.MFCD08691358

*For research and further manufacturing use only, not for direct human use.

2,4-Dichlorothiazole|CS-W018061

Structure of 4175-76-2

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General Information

  • CAS No. 4175-76-2
  • Cat. No. CS-W018061
  • Purity ≥97%
  • MDL No. MFCD08691358
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃HCl₂NS
  • Molecular Weight 154.01
  • Synonym(s) 2,4-Dichloro-thiazole
  • SMILES ClC1=NC(=CS1)Cl

Description

2,4-Dichlorothiazole is a heterocyclic compound featuring two chlorine substituents at the 2- and 4-positions of the thiazole ring. This electron-deficient scaffold integrates readily into synthetic sequences requiring halogen-directed functionalization. The molecule exhibits enhanced stability under standard bench conditions and serves as a key building block in medicinal chemistry and agrochemical development.

Application

2,4-Dichlorothiazole serves as a versatile building block in heterocyclic synthesis, enabling efficient access to thiazole-based scaffolds through palladium-catalyzed cross-coupling and nucleophilic substitution reactions. Its dichloro substitution pattern provides orthogonal reactivity for sequential functionalization, while its bench-stable nature facilitates handling and purification in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.4499
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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