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CS-W001157 4
Total: USD 88.00

2-Bromo-4,6-dimethylaniline

  • CAS No. 41825-73-4

  • Cat. No. CS-W010494
  • Purity≥97%
  • MDL No.MFCD00047826

*For research and further manufacturing use only, not for direct human use.

2-Bromo-4,6-dimethylaniline|CS-W010494

Structure of 41825-73-4

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General Information

  • CAS No. 41825-73-4
  • Cat. No. CS-W010494
  • Purity ≥97%
  • MDL No. MFCD00047826
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀BrN
  • Molecular Weight 200.08
  • Synonym(s) Benzenamine, 2-bromo-4,6-dimethyl-
  • SMILES CC1=CC(Br)=C(N)C(C)=C1

Description

2-Bromo-4,6-dimethylaniline may be used in the synthesis of 2-phenoxy-4,6-dimethylaniline and (4aR,9aR)-4a,6,8-trimethyl-4,4a,9,9a-tetrahydro-1H-carbazol-2(3H)-one.

Application

2-Bromo-4,6-dimethylaniline serves as a valuable building block for the synthesis of substituted anilines and heterocyclic scaffolds. Its bromo group enables facile palladium-catalyzed coupling reactions, while the dimethyl substitution enhances regiochemical control and stability. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for medicinal chemistry campaigns and process-scale applications.

Synthesis

  • Route1
    • null|null
      95-68-1
    • ~92%
    • In-stock
      2-Bromo-4,6-dimethylaniline|CS-W010494
      41825-73-4

    References

    • Kajigaeshi, Shoji; Kakinami, Takaaki; Inoue, Kazuhisa; Kondo, Manabu; Nakamura, Hiroko; et al. Bulletin of the Chemical Society of Japan, 1988 , vol. 61, # 2 p. 597 - 599
  • Route2
    • null|null
      35523-91-2
    • ~%
    • In-stock
      2-Bromo-4,6-dimethylaniline|CS-W010494
      41825-73-4

    References

    • Bamberger Justus Liebigs Annalen der Chemie, 1925 , vol. 443, p. 205
  • Route3
    • null|null
      70853-94-0
    • ~%
    • In-stock
      2-Bromo-4,6-dimethylaniline|CS-W010494
      41825-73-4

    References

    • Bamberger Justus Liebigs Annalen der Chemie, 1921 , vol. 424, p. 300 Justus Liebigs Annalen der Chemie, 1925 , vol. 441, p. 303

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.64814
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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