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Structure of 41926-06-1
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1-Methyl-1H-indazol-7-amine features a methyl-substituted indazole core with a primary amine at the 7-position, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into kinase inhibitor designs and bioactive heterocycles, offering a robust platform for medicinal chemistry optimization.
1-Methyl-1H-indazol-7-amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through palladium-catalyzed cross-coupling and electrophilic substitution reactions. Its moderate basicity and stability under standard reaction conditions facilitate straightforward functionalization at the 7-position, while the indazolyl core provides structural rigidity and hydrogen-bonding capacity valuable in target-directed compound design.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: