3,5-Dimethylpyridin-2-amine

Name: 3,5-Dimethylpyridin-2-amine
Brand: ChemScene
Availability: InStock
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CAS No. 41995-30-6
Cat. No. CS-0005571
Purity≥96%
MDL No.MFCD11040341

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

3,5-Dimethylpyridin-2-amine features a pyridine core with methyl groups at the 3 and 5 positions, enhancing electron density at the nitrogen lone pair. This substitution pattern confers improved solubility and stability in polar solvents while maintaining strong coordination ability. The compound serves as a robust ligand in transition metal catalysis and integrates readily into functionalized heterocycles for pharmaceutical intermediates.

Application

3,5-Dimethylpyridin-2-amine serves as a versatile building block in medicinal chemistry and catalysis, offering enhanced stability and solubility compared to unsubstituted pyridine derivatives. The ortho-dimethyl substitution pattern confers favorable electronic properties and steric protection, enabling reliable coupling reactions and transition metal coordination. Its amine functionality facilitates straightforward derivatization, making it well-suited for the synthesis of kinase inhibitors, ligands, and functionalized heterocycles.

General Information

CAS No. 41995-30-6
Cat. No. CS-0005571
Purity ≥96%
MDL No. MFCD11040341
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₀N₂
Molecular Weight None
Synonym(s) None
SMILES NC1=NC=C(C)C=C1C

Computational Chemistry Data

TPSA 38.91
LogP 1.28064
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P301+P310-P330-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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3,5-Dimethylpyridin-2-amine

CAS No. 41995-30-6

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