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CS-W001157 4
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But-3-yn-2-amine hydrochloride

  • CAS No. 42105-26-0

  • Cat. No. CS-0072301
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

But-3-yn-2-amine hydrochloride|CS-0072301

Structure of 42105-26-0

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Description

But-3-yn-2-amine hydrochloride features a terminal alkyne group conjugated to a primary amine, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC). This bifunctional scaffold integrates seamlessly into bioconjugation workflows and modular synthesis. The hydrochloride salt enhances solubility and stability under standard handling conditions.

Application

But-3-yn-2-amine hydrochloride serves as a versatile building block for alkyne-containing scaffolds, enabling efficient access to functionalized heterocycles via copper-catalyzed cycloadditions and nucleophilic additions. Its amine functionality facilitates straightforward derivatization, while the terminal alkyne supports diverse coupling reactions. The hydrochloride salt enhances bench stability and simplifies handling and purification in standard organic workflows.

General Information

  • CAS No. 42105-26-0
  • Cat. No. CS-0072301
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈ClN
  • Molecular Weight 105.57
  • Synonym(s) but-3-yn-2-amine HCl
  • SMILES C#CC(C)N.Cl

Computational Chemistry Data

  • TPSA   26.02
  • LogP   0.3886
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317
Precautionary Statements : P261-P272-P280-P302+P352-P363-P501

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