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Structure of 4214-28-2
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1-Iodo-2,4-dimethylbenzene features a strategically positioned iodine atom on a methyl-substituted benzene ring, enabling efficient cross-coupling reactions. The ortho-methyl group enhances reactivity while improving stability under standard conditions. This aryl iodide serves as a reliable building block for synthesizing complex biaryl architectures in medicinal chemistry and materials science.
1-Iodo-2,4-dimethylbenzene serves as a versatile aryl iodide building block in palladium-catalyzed cross-coupling reactions. The ortho-methyl groups provide steric and electronic modulation, enhancing stability and directing reactivity in Suzuki, Stille, and Negishi couplings. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing substituted biaryls and complex heterocyclic scaffolds in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: