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Structure of 42454-06-8
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5-Hydroxy-2-nitrobenzaldehyde features a hydroxyl group flanked by a nitro substituent and aldehyde functionality, enabling its use in conjugated systems. This electron-deficient aromatic scaffold integrates readily into synthetic intermediates for dyes, pharmaceuticals, and ligands. The ortho-nitro group enhances reactivity toward nucleophiles while the phenolic OH supports metal coordination.
5-Hydroxy-2-nitrobenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling direct access to substituted benzimidazoles and other heterocyclic scaffolds via condensation reactions. The ortho-nitro and hydroxyl groups provide strong directing effects for electrophilic substitution, while the aldehyde functionality facilitates facile coupling with amines and hydrazines. Bench-stable and compatible with standard purification methods, it functions effectively in multi-step syntheses requiring functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335-H412
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Precautionary Statements : P261-P264-P271-P273-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: