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Structure of 425378-85-4
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This boronate ester features a 4-fluoro-3-methoxyphenyl group coupled to a tetramethyl-1,3,2-dioxaborolane scaffold. It offers enhanced stability and reactivity in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The electron-withdrawing fluorine and methoxy substituents fine-tune reactivity while maintaining excellent bench-stability and moisture tolerance.
2-(4-Fluoro-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its ortho-fluoro and meta-methoxy substituents provide predictable regioselectivity and enhanced functional group tolerance. The tetramethyl-substituted dioxaborolane ring ensures excellent shelf stability and compatibility with aqueous workups, enabling efficient coupling with aryl halides and triflates in diverse synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: