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Structure of 754226-39-6
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This boronate ester features a 3,4-difluorophenyl group linked to a tetramethyl-1,3,2-dioxaborolane scaffold, delivering enhanced stability and reactivity in Suzuki-Miyaura cross-coupling reactions. The electron-withdrawing fluorine substituents modulate electronic properties for improved coupling efficiency, while the steric bulk of the tetramethyl groups ensures bench-stable handling and resistance to hydrolysis under standard conditions.
2-(3,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its tetramethyl-substituted dioxaborolane ring enhances air and moisture stability while maintaining high reactivity with aryl halides and triflates. The 3,4-difluorophenyl moiety offers orthogonal functional group compatibility and enables efficient construction of biaryl scaffolds prevalent in pharmaceutical and agrochemical research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: