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Structure of 42933-44-8
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5-Amino-1-benzofuran-2-carboxylic acid integrates a polar amino group and a carboxylic acid moiety within a fused benzofuran scaffold, enabling direct functionalization in medicinal chemistry. This electron-rich heterocycle supports efficient coupling reactions under mild conditions, facilitating the synthesis of bioactive compounds.
5-Amino-1-benzofuran-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive heterocycles via standard coupling and functionalization protocols. The ortho-amino and carboxylic acid groups provide complementary reactivity for peptide bond formation, amidation, and transition-metal-catalyzed transformations. Bench-stable and readily purified by recrystallization, it functions as a key scaffold for developing kinase inhibitors and other pharmaceutical candidates through established synthetic workflows.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: