3,5-Dimethylpyridin-4-amine

Name: 3,5-Dimethylpyridin-4-amine
Brand: ChemScene
Availability: InStock
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CAS No. 43078-60-0
Cat. No. CS-0006088
Purity≥98%
MDL No.MFCD03413657

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 43078-60-0

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Description

3,5-Dimethylpyridin-4-amine features a pyridine core substituted with methyl groups at the 3 and 5 positions and an amino group at the 4 position, conferring enhanced electron density and improved solubility in polar solvents. This combination imparts strong nucleophilicity and stability under standard bench conditions, enabling efficient incorporation into catalyst scaffolds and bioactive molecule frameworks.

Application

3,5-Dimethylpyridin-4-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its pyridine core exhibits favorable electronic properties and bench stability, while the ortho-methyl groups enhance metabolic resistance. The amine functionality facilitates direct derivatization and salt formation, supporting purification and solubility optimization in synthetic workflows.

General Information

CAS No. 43078-60-0
Cat. No. CS-0006088
Purity ≥98%
MDL No. MFCD03413657
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₀N₂
Molecular Weight 122.17
Synonym(s) 4-Amino-3,5-dimethylpyridine
SMILES NC1=C(C)C=NC=C1C

Computational Chemistry Data

TPSA 38.91
LogP 1.28064
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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3,5-Dimethylpyridin-4-amine

CAS No. 43078-60-0

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