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CS-W001157 4
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Sodium 2-(methylamino)acetate

  • CAS No. 4316-73-8

  • Cat. No. CS-0077129
  • Purity40% in water
  • MDL No.MFCD00068282

*For research and further manufacturing use only, not for direct human use.

Sodium 2-(methylamino)acetate|CS-0077129

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General Information

  • CAS No. 4316-73-8
  • Cat. No. CS-0077129
  • Purity 40% in water
  • MDL No. MFCD00068282
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₆NNaO₂
  • Molecular Weight 111.08
  • Synonym(s) Sodium Sarcosine
  • SMILES [Na].O=C(O)CNC

Description

Sodium 2-(methylamino)acetate, 40% in water delivers a stable, moisture-tolerant source of the methylaminoacetic acid anion. This aqueous solution features enhanced solubility and handling convenience for synthetic applications requiring basic nitrogen functionality. Ideal for peptide derivatization and reagent synthesis under standard conditions.

Application

Sodium 2-(methylamino)acetate, 40% in water serves as a stable, readily handled source of the methylaminoacetic acid anion, enabling efficient access to β-amino acid derivatives. Its aqueous formulation facilitates direct use in peptide coupling and heterocycle synthesis, with demonstrated compatibility in standard amide bond formation and nucleophilic substitution reactions. The compound exhibits good bench stability and simplifies purification in multi-step sequences.

Synthesis

  • Route1

    References

    • Thalhammer, Franz; Gastner, Thomas Patent: US2009/163739 A1, 2009 ; Location in patent: Page/Page column 2 ;
  • Route2

    References

    • Voss; Guttmann Chemische Berichte, 1930 , vol. 63, p. 1731

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   -1.3581
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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