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CS-W001157 4
Total: USD 88.00

2-Nitrobenzenesulfonyl fluoride

  • CAS No. 433-98-7

  • Cat. No. CS-0181567
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

2-Nitrobenzenesulfonyl fluoride|CS-0181567

Structure of 433-98-7

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Description

2-Nitrobenzenesulfonyl fluoride is a bench-stable, moisture-tolerant reagent featuring a strongly electron-deficient sulfonyl group paired with a para-nitro aryl moiety. This combination enhances electrophilicity for efficient sulfonation and fluorination reactions in synthetic workflows. The reagent integrates cleanly into multistep sequences requiring selective functionalization under mild conditions.

Application

2-Nitrobenzenesulfonyl fluoride serves as a highly effective sulfonating agent and electrophilic fluorinating reagent in synthetic organic chemistry. It enables efficient introduction of sulfonyl and fluorine functionalities under mild conditions, with demonstrated utility in the preparation of sulfonamide derivatives and fluorinated heterocycles. Its bench-stable nature and compatibility with diverse functional groups make it a practical choice for medicinal chemistry and process development workflows.

General Information

  • CAS No. 433-98-7
  • Cat. No. CS-0181567
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄FNO₄S
  • Molecular Weight 205.16
  • Synonym(s) O-NITROBENZENESULFONYL FLUORIDE
  • SMILES O=S(C1=CC=CC=C1[N+]([O-])=O)(F)=O

Computational Chemistry Data

  • TPSA   77.28
  • LogP   1.253
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group :
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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