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CS-W001157 4
Total: USD 88.00

2,2,2-Trifluoro-1-phenylethan-1-one

  • CAS No. 434-45-7

  • Cat. No. CS-0031430
  • Purity≥98%
  • MDL No.MFCD00000420

*For research and further manufacturing use only, not for direct human use.

2,2,2-Trifluoro-1-phenylethan-1-one|CS-0031430

Structure of 434-45-7

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General Information

  • CAS No. 434-45-7
  • Cat. No. CS-0031430
  • Purity ≥98%
  • MDL No. MFCD00000420
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅F₃O
  • Molecular Weight 174.12
  • Synonym(s) Trifluoroacetophenone
  • SMILES FC(F)(F)C(C1=CC=CC=C1)=O

Description

2,2,2-Trifluoroacetophenone is the starting material for the synthesis of f 3-trifluoromethyl-3-phenyldiazirine. It undergoes asymmetric reduction with optically active Grignard reagent to form 2,2,2-trifluoro-1-phenylethanol. It undergoes condensation with biphenyl, terphenyl, a mixture of biphenyl with terphenyl, phenyl ether and diphenoxybenzophenone to form new aromatic 3F polymers.2,2,2-trifluoroacetophenone is used as an organocatalyst for the oxidation of tertiary amines and azines to N-oxidesalkenes.2,2,2-Trifluoroacetophenone was used in the synthesis of new fluorinated polymers, having high average molecular weight, high thermal stability and good film-forming properties.

Synthesis

  • Route1
    • null|null
      93-58-3
    • null|null
      75-46-7
    • ~69%
    • In-stock
      2,2,2-Trifluoro-1-phenylethan-1-one|CS-0031430
      434-45-7

    References

    • Russell, Jamie; Roques, Nicolas Tetrahedron, 1998 , vol. 54, # 45 p. 13771 - 13782
  • Route2
    • null|null
      353-85-5
    • null|null
      71-43-2
    • ~85%
    • In-stock
      2,2,2-Trifluoro-1-phenylethan-1-one|CS-0031430
      434-45-7

    References

    • Raja, Erum K.; Klumpp, Douglas A. Tetrahedron Letters, 2011 , vol. 52, # 40 p. 5170 - 5172
  • Route3
    • null|null
      75-46-7
    • null|null
      98-88-4
    • ~78%
    • In-stock
      2,2,2-Trifluoro-1-phenylethan-1-one|CS-0031430
      434-45-7
    • In-stock
      1,1,1,3,3,3-Hexafluoro-2-phenylpropan-2-ol|CS-W012743
      718-64-9

    References

    • Zhang, Yuan; Fujiu, Motohiro; Serizawa, Hiroki; Mikami, Koichi Journal of Fluorine Chemistry, 2013 , vol. 156, p. 367 - 371

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1224
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.4316
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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