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CS-W001157 4
Total: USD 88.00

4-(3-Bromophenyl)pyridine

  • CAS No. 4373-72-2

  • Cat. No. CS-0156967
  • Molecule weight234.09
  • Purity≥98%
  • MDL No.MFCD16250222

*For research and further manufacturing use only, not for direct human use.

4-(3-Bromophenyl)pyridine|CS-0156967

Structure of 4373-72-2

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General Information

  • CAS No. 4373-72-2
  • Cat. No. CS-0156967
  • Purity ≥98%
  • MDL No. MFCD16250222
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₈BrN
  • Molecular Weight 234.09
  • Synonym(s) 1-Bromo-3-(4-pyridyl)benzene
  • SMILES C1=CC(=CC(=C1)Br)C2=CC=NC=C2

Description

4-(3-Bromophenyl)pyridine features a brominated phenyl ring coupled to a pyridine heterocycle, enabling seamless integration into cross-coupling reactions. This electron-deficient aryl halide serves as a robust scaffold for constructing advanced materials and functional molecules in medicinal chemistry and catalysis.

Application

4-(3-Bromophenyl)pyridine serves as a versatile building block in cross-coupling reactions, enabling efficient construction of biaryl scaffolds under standard Pd-catalyzed conditions. The bromo substituent exhibits high reactivity in Suzuki, Stille, and Negishi couplings, while the pyridine nitrogen provides orthogonal functionality for further derivatization. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.5111
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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