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Structure of 4387-36-4
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2-Iodobenzonitrile serves as a pivotal building block in cross-coupling chemistry, featuring a strategically positioned iodide and nitrile group for orthogonal reactivity. This bench-stable aryl halide enables efficient palladium-catalyzed transformations, integrating seamlessly into the synthesis of functionalized biaryls and heterocyclic scaffolds under standard conditions.
2-Iodobenzonitrile serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient C–C and C–heteroatom bond formation. Its iodine functionality offers high reactivity in Pd- or Ni-catalyzed processes, while the nitrile group provides orthogonal handle for further derivatization. Bench-stable and readily purified by recrystallization, it facilitates reliable synthesis of substituted benzonitriles, heterocyclic scaffolds, and functionalized aryl intermediates in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: