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Structure of 440100-94-7
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2-Bromothiazole-5-carbonitrile features a bromine atom at the 2-position and a nitrile group at the 5-position on a thiazole scaffold. This electron-deficient heterocycle enables direct coupling in cross-coupling reactions, serving as a key building block for pharmaceutical intermediates and functional materials.
2-Bromothiazole-5-carbonitrile serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its compatible bromine and nitrile functionalities. The molecule exhibits good bench stability and facilitates the construction of thiazole-based heterocycles, commonly found in bioactive scaffolds. Its dual reactive sites allow for sequential functionalization, supporting efficient synthesis of complex intermediates with high regiocontrol.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: