cis-4-Hydroxy-L-proline hydrochloride

Name: cis-4-Hydroxy-L-proline hydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 441067-49-8
Cat. No. CS-0028245
Purity≥97%
MDL No.MFCD09953187

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

cis-4-Hydroxy-L-proline hydrochloride|CS-0028245

Structure of 441067-49-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

cis-4-Hydroxy-L-proline (hydrochloride) delivers a stabilized, moisture-tolerant form of the bioactive proline derivative, featuring a cis-configured hydroxyl group critical for collagen mimicry. This bench-stable variant simplifies handling in peptide synthesis and structural studies, enabling reliable incorporation into polypeptide scaffolds where precise stereochemistry governs conformational integrity.

Application

cis-4-Hydroxy-L-proline (hydrochloride) serves as a key building block in the synthesis of bioactive peptides and natural product analogs, offering enhanced conformational rigidity due to its cis-configured hydroxyl group. The hydrochloride salt improves solubility and handling stability, facilitating straightforward incorporation into solid-phase peptide synthesis workflows. Its well-documented role in stabilizing type I collagen-like structures makes it valuable for medicinal chemistry projects targeting extracellular matrix-related therapeutics.

General Information

CAS No. 441067-49-8
Cat. No. CS-0028245
Purity ≥97%
MDL No. MFCD09953187
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₀ClNO₃
Molecular Weight 167.59
Synonym(s) None
SMILES [H]Cl.O=C(O)[C@H]1NC[C@@H](O)C1

Computational Chemistry Data

TPSA 69.56
LogP -0.7844
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Proline and derivatives

Life Science ADC Related Compound Non-cleavable linker

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Biochemistry Pharmaceutical Development and Drug Discovery Research Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Key Words

cis-4-Hydroxy-L-proline hydrochloride sigmacis-4-Hydroxy-L-proline hydrochloride manufacturercis-4-Hydroxy-L-proline hydrochloride pricecis-4-Hydroxy-L-proline hydrochloride structurecis-4-Hydroxy-L-proline hydrochloride SDSbuy cis-4-Hydroxy-L-proline hydrochloridecis-4-Hydroxy-L-proline hydrochloride suppliercis-4-Hydroxy-L-proline hydrochloride usescis-4-Hydroxy-L-proline hydrochloride molecular weightprice of cis-4-Hydroxy-L-proline hydrochloridecis-4-Hydroxy-L-proline hydrochloride chemical name formula of cis-4-Hydroxy-L-proline hydrochloride

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

cis-4-Hydroxy-L-proline hydrochloride

CAS No. 441067-49-8

Recommended Products