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CS-W001157 4
Total: USD 88.00

Piperonylonitrile

  • CAS No. 4421-09-4

  • Cat. No. CS-D1495
  • Purity≥97%
  • MDL No.MFCD00005820
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Piperonylonitrile|CS-D1495

Structure of 4421-09-4

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Description

Piperonylonitrile features a rigid, electron-deficient aromatic core paired with a reactive nitrile group, enabling efficient coupling in synthetic transformations. This bench-stable compound integrates readily into heterocyclic architectures and serves as a key building block in agrochemical and pharmaceutical synthesis.

Application

Piperonylonitrile serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of bioactive heterocycles and pharmaceutical intermediates. Its ortho-allylbenzene scaffold supports diverse transformations including cycloadditions, electrophilic substitutions, and transition-metal-catalyzed couplings. The nitrile group provides a handle for selective functionalization, while the molecule exhibits excellent bench stability and compatibility with common protecting groups, facilitating streamlined purification and scale-up.

General Information

  • CAS No. 4421-09-4
  • Cat. No. CS-D1495
  • Purity ≥97%
  • MDL No. MFCD00005820
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅NO₂
  • Molecular Weight 147.13
  • Synonym(s) None
  • SMILES N#CC1=CC=C(OCO2)C2=C1

Computational Chemistry Data

  • TPSA   42.25
  • LogP   1.28698
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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