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Structure of 444-29-1
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2-Iodobenzotrifluoride serves as a key arylating agent in transition metal-catalyzed cross-coupling reactions. The trifluoromethyl group imparts enhanced electron-withdrawing character and metabolic stability, while the iodine handle enables efficient palladium-mediated functionalization. This compound exhibits excellent bench stability and compatibility with diverse reaction conditions.
2-Iodobenzotrifluoride serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl architectures. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, making it valuable for medicinal chemistry applications. The iodine moiety facilitates reliable Suzuki, Stille, and Negishi couplings under standard conditions, while the compound exhibits good bench stability and ease of handling.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: