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Structure of 4442-94-8
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2-Cyclohexyl-2-hydroxyacetic acid features a cyclohexyl group flanking a hydroxylated acetic acid core, delivering enhanced lipophilicity and metabolic stability. This structural motif enables direct integration into bioactive scaffolds, serving as a robust building block for pharmaceutical intermediates and functionalized polymers under standard conditions.
2-Cyclohexyl-2-hydroxyacetic acid serves as a versatile chiral building block in synthetic organic chemistry, enabling the construction of biologically relevant heterocyclic scaffolds and functionalized alcohols. Its α-hydroxy acid functionality facilitates stereoselective transformations, including esterification, amidation, and cyclization reactions. The cyclohexyl group provides enhanced lipophilicity and conformational rigidity, improving metabolic stability in downstream applications. Bench-stable and readily purified by recrystallization, it functions effectively in both laboratory-scale synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: