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Structure of 445305-91-9
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Cyclobutanesulfonamide delivers a rigid, strained sulfonamide moiety ideal for probing bioisosteric effects in medicinal chemistry. This bench-stable compound features a cyclobutane ring that imparts unique conformational restraint, enhancing target binding affinity. Its moisture-tolerant nature simplifies handling in synthetic workflows.
Cyclobutanesulfonamide serves as a stable, bench-ready sulfonamide building block for medicinal chemistry and synthetic applications. Its rigid cyclobutane scaffold imparts conformational constraint, enabling precise spatial orientation in target molecules. The sulfonamide group exhibits strong hydrogen-bonding capacity and metabolic stability, facilitating interactions with biological targets. It reacts predictably with nucleophiles and participates reliably in amide coupling protocols, offering orthogonal functionalization potential in complex molecule assembly.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: