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Structure of 446-61-7
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2-Fluoro-6-methoxyaniline features a fluorine atom at the ortho position and a methoxy group at the para position relative to the amine, creating a uniquely electron-rich aromatic scaffold. This combination imparts enhanced solubility in polar solvents and improved stability under standard bench conditions. The molecule integrates readily into pharmaceutical intermediates and functional materials via coupling reactions.
2-Fluoro-6-methoxyaniline serves as a valuable building block in medicinal chemistry, enabling the construction of fluorinated heterocycles and bioactive scaffolds. Its ortho-fluoro and para-methoxy substituents provide enhanced metabolic stability and modulated electronic properties, while the primary amine facilitates straightforward derivatization via acylation, alkylation, or coupling reactions. Bench-stable and readily purified by crystallization, it functions effectively in standard amine-based transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: