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Structure of 447-61-0
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2-(Trifluoromethyl)benzaldehyde has been used in the preparation of:-(dimethylamino)-alkylethyl-4(-2-(trifluorormethyl)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylatesmethyl (E)-2-[2-[(E)-2-(2-trifluoromethylphenyl)vinyl]-phenyl]-3-methoxyacrylate via Wittig-Horner reaction
2-(Trifluoromethyl)benzaldehyde serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering a highly electron-deficient aromatic aldehyde with enhanced metabolic stability. Its trifluoromethyl group imparts strong lipophilicity and resistance to oxidative degradation, while the aldehyde functionality enables diverse transformations including nucleophilic additions, imine formations, and Wittig reactions. The compound exhibits excellent bench stability and is compatible with standard purification methods, facilitating its use in multi-step syntheses of bioactive heterocycles and functionalized aryl scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H315-H319-H335
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Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: