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Structure of 577-62-8
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Ethyl 2-(trifluoromethyl)benzoate features a trifluoromethyl group that imparts enhanced electron-withdrawal and metabolic stability. This aromatic ester integrates readily into synthetic sequences requiring robust, fluorinated building blocks. The ester functionality enables straightforward derivatization under standard conditions.
Ethyl 2-(trifluoromethyl)benzoate serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling efficient access to biologically relevant heterocycles and functionalized aromatic scaffolds. Its trifluoromethyl group enhances metabolic stability and modulates lipophilicity, while the ester functionality facilitates downstream transformations such as hydrolysis, reduction, or coupling reactions. Bench-stable and readily purified by standard chromatographic methods, it functions reliably in cross-coupling, nucleophilic substitution, and transition-metal-catalyzed processes.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: