2-Chloro-4,6-dimethylpyrimidine

Name: 2-Chloro-4,6-dimethylpyrimidine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 4472-44-0
Cat. No. CS-W007770
Purity≥98%
MDL No.MFCD00023199

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chloro-4,6-dimethylpyrimidine|CS-W007770

Structure of 4472-44-0

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2-Chloro-4,6-dimethylpyrimidine is a bench-stable, moisture-tolerant heterocyclic building block featuring a chlorine atom at the 2-position and methyl groups at the 4- and 6-positions. This electronic configuration enhances its reactivity in nucleophilic substitution processes, enabling efficient coupling with amines and thiols to form functionalized pyrimidine derivatives. The molecule's steric profile supports selective transformations, streamlining access to advanced intermediates in medicinal chemistry and agrochemical synthesis.

Application

2-Chloro-4,6-dimethylpyrimidine serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient construction of pyrimidine-based scaffolds. Its chloro group facilitates nucleophilic substitution reactions with amines, thiols, and other soft nucleophiles under mild conditions. The methyl substituents enhance stability and modulate electronic properties, while the compound exhibits excellent bench stability and ease of purification—ideal for use in multi-step syntheses and API intermediate development.

General Information

CAS No. 4472-44-0
Cat. No. CS-W007770
Purity ≥98%
MDL No. MFCD00023199
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇ClN₂
Molecular Weight 142.59
Synonym(s) Pyrimidine, 2-chloro-4,6-dimethyl-; 2-Chloro-4,6-dimethylpyrimidine
SMILES CC1=CC(C)=NC(Cl)=N1

Computational Chemistry Data

TPSA 25.78
LogP 1.74684
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

2-Chloro-4,6-dimethylpyrimidine sigma2-Chloro-4,6-dimethylpyrimidine manufacturer2-Chloro-4,6-dimethylpyrimidine price2-Chloro-4,6-dimethylpyrimidine structure2-Chloro-4,6-dimethylpyrimidine SDSbuy 2-Chloro-4,6-dimethylpyrimidine2-Chloro-4,6-dimethylpyrimidine supplier2-Chloro-4,6-dimethylpyrimidine uses2-Chloro-4,6-dimethylpyrimidine molecular weightprice of 2-Chloro-4,6-dimethylpyrimidine2-Chloro-4,6-dimethylpyrimidine chemical name formula of 2-Chloro-4,6-dimethylpyrimidine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-4,6-dimethylpyrimidine

CAS No. 4472-44-0

Recommended Products