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Structure of 455-14-1
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4-(Trifluoromethyl)aniline was used in the synthesis of 4-(trialkylmethyl)anilines. It was also used as a synthetic building block.
4-(Trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry and materials science, enabling direct incorporation of the electron-withdrawing trifluoromethyl group into aromatic scaffolds. Its stability under standard reaction conditions and compatibility with common coupling protocols facilitate efficient access to functionalized anilines. The molecule functions effectively in Suzuki-Miyaura, Ullmann, and Buchwald-Hartwig couplings, offering reliable routes to biaryl systems and heterocyclic architectures relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS05,GHS06,GHS09
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H318-H410
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Precautionary Statements : P264-P270-P273-P280-P330-P391-P405-P501
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Lot numbers can be found on the outside label of a product: