Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-tert-Butylimidazole

  • CAS No. 45676-04-8

  • Cat. No. CS-0154875
  • Purity≥97%
  • MDL No.MFCD19441219

*For research and further manufacturing use only, not for direct human use.

1-tert-Butylimidazole|CS-0154875

Structure of 45676-04-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 45676-04-8
  • Cat. No. CS-0154875
  • Purity ≥97%
  • MDL No. MFCD19441219
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂N₂
  • Molecular Weight 124.18
  • Synonym(s) 1-tert-Butyl-1H-imidazole
  • SMILES CC(C)(C)N1C=CN=C1

Description

1-tert-Butylimidazole is a sterically hindered imidazole derivative featuring a bulky tert-butyl group at the 1-position. This substitution enhances solubility in organic media and imparts exceptional bench stability. The molecule serves as a robust, moisture-tolerant base in catalytic transformations and functional group manipulations, particularly in palladium-catalyzed cross-coupling reactions where minimizing side pathways is critical.

Application

1-tert-Butylimidazole serves as a robust, bench-stable nitrogen heterocycle widely employed in synthetic chemistry. Its sterically hindered imidazole core enables selective deprotonation and acts as a versatile base and nucleophilic catalyst in coupling reactions. The tert-butyl group enhances solubility and reduces unwanted side reactivity, facilitating purification and improving functional group tolerance in complex molecule synthesis.

Synthesis

  • Route1
    • null|null
      50-00-0
    • null|null
      131543-46-9
    • null|null
      75-64-9
    • ~67%
    • In-stock
      1-tert-Butylimidazole|CS-0154875
      45676-04-8

    References

    • Sauerbrey, Susanne; Majhi, Paresh Kumar; Daniels, Joerg; Schnakenburg, Gregor; Bmndle, Gerhard Markus; Scherer, Katharina; Streubel, Rainer Inorganic Chemistry, 2011 , vol. 50, # 3 p. 793 - 799
  • Route2
    • Imidazole Ondansetron Impurity|CS-0229601
      288-32-4
    • null|null
      507-19-7
    • ~84%
    • In-stock
      1-tert-Butylimidazole|CS-0154875
      45676-04-8

    References

    • Yang, Xiao-Dong; Zeng, Xiang-Hui; Zhang, Yan-Li; Qing, Chen; Song, Wen-Jian; Li, Liang; Zhang, Hong-Bin Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 7 p. 1892 - 1895
  • Route3

    References

    • Cassidy, Constance S.; Reinhardt, Laurie A.; Cleland, W. Wallace; Frey, Perry A. Journal of the Chemical Society. Perkin Transactions 2, 1999 , # 3 p. 635 - 641

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   17.82
  • LogP   1.6381
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-tert-Butylimidazole sigma1-tert-Butylimidazole manufacturer1-tert-Butylimidazole price1-tert-Butylimidazole structure1-tert-Butylimidazole SDSbuy 1-tert-Butylimidazole1-tert-Butylimidazole supplier1-tert-Butylimidazole uses1-tert-Butylimidazole molecular weightprice of 1-tert-Butylimidazole1-tert-Butylimidazole chemical name formula of 1-tert-Butylimidazole
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label