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Structure of 45676-04-8
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1-tert-Butylimidazole is a sterically hindered imidazole derivative featuring a bulky tert-butyl group at the 1-position. This substitution enhances solubility in organic media and imparts exceptional bench stability. The molecule serves as a robust, moisture-tolerant base in catalytic transformations and functional group manipulations, particularly in palladium-catalyzed cross-coupling reactions where minimizing side pathways is critical.
1-tert-Butylimidazole serves as a robust, bench-stable nitrogen heterocycle widely employed in synthetic chemistry. Its sterically hindered imidazole core enables selective deprotonation and acts as a versatile base and nucleophilic catalyst in coupling reactions. The tert-butyl group enhances solubility and reduces unwanted side reactivity, facilitating purification and improving functional group tolerance in complex molecule synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: