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Structure of 459448-06-7
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6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine features a fused triazolopyridine core with a bromine at the 6-position and a sterically hindered isopropyl group at the 3-position. This combination imparts enhanced stability and directs regioselective functionalization in cross-coupling reactions. The electron-deficient heterocycle facilitates efficient palladium-catalyzed transformations, making it a valuable scaffold for medicinal chemistry and materials science applications.
6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromine handle. The isopropyl group enhances steric and electronic stability, improving shelf life and facilitating purification. This scaffold functions effectively in the synthesis of triazolopyridine-based heterocycles, commonly found in kinase inhibitors and other bioactive molecules, with broad compatibility in standard coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: