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Structure of 461-52-9
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3,3-Difluoropropan-1-ol features a fluorinated alkyl chain that enhances metabolic stability and lipophilicity. This bench-stable alcohol integrates readily into bioactive scaffolds, offering improved membrane permeability. The geminal difluoro substitution imparts unique electronic effects, enabling precise tuning of reactivity in synthetic transformations.
3,3-Difluoropropan-1-ol serves as a valuable fluorinated building block in medicinal chemistry, enabling the introduction of a stable difluoromethylene motif adjacent to a primary alcohol. Its bench-stable nature and compatibility with standard functional group manipulations facilitate efficient synthesis of bioactive molecules, particularly in the construction of fluorinated heterocycles and metabolically resistant analogs.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H225-H315-H319
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Precautionary Statements : P210-P280-P302+P352-P362-P370+P378
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Lot numbers can be found on the outside label of a product: