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Structure of 461699-81-0
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2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline features a boronate ester group enabling robust Suzuki-Miyaura coupling under mild conditions. The methoxy substituent enhances electron density at the aromatic ring, improving reactivity in cross-coupling reactions. This bench-stable compound integrates seamlessly into complex molecular architectures with minimal purification needs.
2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The ortho-methoxy group provides electronic modulation and enhances solubility, while the pinacol boronate ester offers excellent stability and compatibility with diverse reaction conditions. It facilitates efficient C–C bond formation under mild catalytic conditions, enabling rapid access to substituted anilines and biaryl scaffolds in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: