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Structure of 46249-41-6
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4-(Aminosulfonyl)benzenesulfonyl chloride features a dual sulfonyl architecture with a terminal amine, enabling direct conjugation to biomolecules and polymers. This electrophilic reagent facilitates site-specific labeling under mild conditions, offering high reactivity toward nucleophiles while maintaining stability during storage.
4-(Aminosulfonyl)benzenesulfonyl chloride serves as a versatile bifunctional building block for constructing sulfonamide-containing scaffolds. Its reactive sulfonyl chloride group enables efficient coupling with amines to form stable sulfonamide linkages, while the pendant aminosulfonyl moiety offers additional sites for derivatization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and API development workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: