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Structure of 4679-87-2
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This indolone derivative features a sterically hindered isopropyl group at the 3-position, enhancing stability and modulating reactivity. The scaffold integrates readily into complex heterocyclic systems, offering a robust platform for medicinal chemistry exploration and synthetic diversification under standard conditions.
3-Isopropyl-1,3-dihydroindol-2-one serves as a versatile scaffold in medicinal chemistry, enabling efficient access to indole-based heterocycles. Its functional group tolerance facilitates downstream derivatization via standard coupling and cyclization protocols. The isopropyl substituent enhances metabolic stability and modulates lipophilicity, improving bioavailability profiles. Bench-stable and readily purified by flash chromatography, it functions as a reliable building block for API intermediates and drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: